Glucosamine
Amino sugar component of cartilage. Used for knee osteoarthritis. The sulfate form is the most studied. Study results are mixed.
💡 Absorption: Glucosamine sulfate 1500mg/day is the standard dose. Crystalline glucosamine sulfate (Rottapharm) has better studies than the HCl form.
⚠️ Caution: Derived from shellfish: contraindicated in shellfish allergy (except vegetarian forms). May affect blood glucose in diabetics. Interacts with warfarin.
📚 Scientific references (4)▼
Revision sistematica actualizada. Glucosamina sulfato cristalino tiene mejor evidencia que HCl.
Meta-analisis. La combinacion glucosamina+condroitina reduce dolor de rodilla significativamente vs tratamiento rutinario.
Meta-analisis de RCTs con placebo. Glucosamina y condroitina reducen dolor (VAS) significativamente.
GAIT trial (1583 pacientes). Glucosamina+condroitina no supero placebo en general pero si en subgrupo con dolor moderado-severo.
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